ABSTRACT
Background: Association of idiopathic inflammatory myopathies (IIM) with malignancy has been well- recognized for a long time. However, its association with the novel corona virus (COVID-19) infection is extremely rare. Here we report a case of polymyositis in a patient with COVID-19 infection with underlying colorectal cancer. Case Presentation: Here we report a case of a 73-year-old male who was admitted for COVID-19 infection but developed persistent limb weakness which was finally diagnosed as polymyositis. He was given high dose steroid along with methotrexate to which he responded very well. Conclusions: Inflammatory myopathy should be suspected in elderly patients who present with generalized weakness especially in the background of malignancy. The association of COVID-19 infection with myositis needs further studies.